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ChemicalBook CAS DataBase List Ethyl 5-bromovalerate
14660-52-7

Ethyl 5-bromovalerate synthesis

9synthesis methods
-

Yield:-

Reaction Conditions:

with thionyl chloride in ethanol

Steps:

14.A Di-[(5-N,N-dibutylamino)pentyl] carbonate dihydrochloride hydrate
A] Starting from 5-bromopentanoic acid (50 g, 0.276 mole) and thionyl chloride (39 ml, 0.552 mole) in absolute ethanol (500 ml) and following the procedure of Example 13,A], there were obtained 62.7 g of ethyl 5-bromopentanoate (quantitative yield) which was used as such in the next step.

References:

ITALFARMACO S.p.A. EP748310, 1999, B1

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