ChemicalBook CAS DataBase List Ethyl 3-mercaptopropionate

Ethyl 3-mercaptopropionate synthesis

9synthesis methods

Product Name:Ethyl 3-mercaptopropionate
CAS Number:5466-06-8
Molecular formula:C5H10O2S
Molecular Weight:134.2

64-17-5 Synthesis

64-17-5
724 suppliers
$10.00/50g

107-96-0
541 suppliers
$6.00/25g

5466-06-8
176 suppliers
$66.00/25g

Yield:5466-06-8 94.2%

Reaction Conditions:

with 1-methyl-3-(3-sulfopropyl)imidazol-3-ium hydrogen sulfate at 80; for 0.0111111 h;Flow reactor;Large scale;

Steps:

5 Example 5

Weigh 3475 g of ethanol, 2000 g of 3-mercaptopropionic acid, and 100 g of catalyst, mix 3-mercaptopropionic acid and the catalyst evenly, and pump the ethanol and 3-mercaptopropionic acid catalyst solution into the microchannel reactor respectively, and carry out at 80 ° C. To react, adjust the feeding speed of the pump, control the molar ratio of 3-mercaptopropionic acid and ethanol to be 1:4, and the residence time to be 40 seconds, the boiling point of ethanol has been reached, and a back pressure of 0.3-0.5MPa is required.After receiving the reaction material, the liquid was left to stand for stratification, and the upper layer reaction liquid was distilled and separated to obtain 2379.5 g of ethyl 3-mercaptopropionate, and the calculated yield was 94.2%.The mass of the dehydrated lower ionic liquid was 218 g, and the content of 3-mercaptopropionic acid was 53.2% by quantitative analysis.

References:

CN114773241,2022,A Location in patent:Paragraph 0028-0029