ChemicalBook CAS DataBase List DIPHENYL-N-PROPYLPHOSPHINE

DIPHENYL-N-PROPYLPHOSPHINE synthesis

10synthesis methods

Product Name:DIPHENYL-N-PROPYLPHOSPHINE
CAS Number:7650-84-2
Molecular formula:C15H17P
Molecular Weight:228.27

540-54-5 Synthesis

540-54-5
214 suppliers
$18.00/25mL

603-35-0 Synthesis

603-35-0
711 suppliers
$5.00/5 g

103-65-1
168 suppliers
$17.00/25mL

7650-84-2
95 suppliers
$12.00/1g

Yield: 91.6% ， 93.5%

Reaction Conditions:

Stage #1:triphenylphosphine with lithium in tetrahydrofuran at 20; for 3 h;Inert atmosphere;
Stage #2:1-Chloropropane in tetrahydrofuran at 5 - 50; for 6.25 h;

Steps:

7
1) Under the protection of nitrogen, triphenylphosphine was added to the reaction flask equipped with tetrahydrofuran, and the molar ratio of metal lithium to triphenylphosphine was 2.2: 1 under stirring. The reaction was carried out at room temperature for 3 hours To ensure that the reaction of the triphenylphosphine is complete, the unreacted metal lithium is removed and removed to obtain a phenylphosphoric lithium tetrahydrofuran solution;2) The solution of the obtained phenylphosphine lithium tetrahydrofuran in step 1) was cooled to 5 ° C, and chloropropane was added dropwise to the system,15min after the drop, the insulation reaction 3h, then the system temperature to 50 , insulation reaction 3h, the system down to room temperature, add water, stirring after the static layer, remove the water layer, dry; distillation of tetrahydrofuran, and then decompression Distillation, respectively dipropyl diphenyl phosphine and propyl benzene.The method for producing alkyl diphenyl phosphines in the present embodiment for producing alkylbenzene, the yield of propyl diphenylphosphine is91.6% and the yield of propylbenzene was 93.5%.

References:

Zhang Yuqing CN105111235, 2017, B Location in patent:Paragraph 0082; 0084-0087

106-94-5 Synthesis