ChemicalBook CAS DataBase List Dibutyl phthalate

Dibutyl phthalate synthesis

9synthesis methods

Product Name:Dibutyl phthalate
CAS Number:84-74-2
Molecular formula:C16H22O4
Molecular Weight:278.34

Dibutyl phthalate is produced from n-butanol and phthalic anhydride in an ester formation reaction.

85-44-9 Synthesis

85-44-9
765 suppliers
$9.00/5g

71-36-3 Synthesis

71-36-3
1044 suppliers
$14.00/25mL

84-74-2
813 suppliers
$14.69/5g

Yield:84-74-2 100%

Reaction Conditions:

with diacidic ionic liquid supported on magnetic-silica nanoparticles in neat (no solvent) at 118; for 2 h;Dean-Stark;Temperature;

Steps:

Typical procedure for diesterification of 2-methoxyethanol by SDAIL magnetic nanoSiO2 as catalyst

The required amounts of phthalic anhydride (1 mmol, 0.15 g), 2-methoxyethanol (5 mmol, 0.39 mL, 0.38 g) and SDAILmagnetic nanoSiO2as catalyst (10 wt% to phthalic anhydride, 0.01 g) were added successively into a 50 mL round bottom flask with a dean-stark apparatus, reflux condenser and a magnetic stirrer. The esterification reaction was allowed to proceed at 130 °C for 8 h under vigorous stirring. The completion of reaction was monitored by TLC using(EtOAC/Hexane 2:8) as eluent. After completion of the reaction, the catalyst was recovered from the reaction mixture using an external magnet and subjected to drying under high vacuum at 70 C for 6 h to remove water, leaving behind the SDAILatmagnetic nanoSiO2 (recovery 98%) which was recycled. Then, the product (bis(2-methoxyethyl) phthalate)was separated simply by extraction with ethyl acetate(3 × 5 mL) and ethyl acetate was evaporated under vacuum to afford desired product as colorless oily liquid at 98% yield(0/25 g, boiling point = 340 °C). The obtained product dried under vacuum at 70 °C for 6 h.

References:

Fareghi-Alamdari, Reza;Nadiri Niri, Mehri;Hazarkhani, Hassan;Zekri, Negar [Journal of the Iranian Chemical Society,2018,vol. 15,# 11,p. 2615 - 2629]

201230-82-2 Synthesis