BOC-4-OXO-L-PROLINE TERT-BUTYL ESTER synthesis
- Product Name:BOC-4-OXO-L-PROLINE TERT-BUTYL ESTER
- CAS Number:166410-05-5
- Molecular formula:C14H23NO5
- Molecular Weight:285.34
170850-75-6
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$75.70/250MG
166410-05-5
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$55.00/1g
Yield: 92.74%
Reaction Conditions:
with 4-methylmorpholine N-oxide in dichloromethane at 20; for 1.5 h;Reagent/catalyst;
Steps:
1.2
(2) 17.36 g of the compound hydrazine was dissolved in dichloromethane, and 9.45 g of N-methyl_N_oxidized morpholine was added and stirred at room temperature for 1.5 hours, and the reaction completely gave a black turbid liquid, and the reaction solution was filtered off to remove insoluble matter. The filtrate was evaporated to dryness and purified by column chromatography to yield 16.75 g of white solid compound m, yield 92.74%
References:
Tierxi (Nanjing) Pharmaceutical Research And Development Co., Ltd.;He Xu;Wang Jiayan;Zhang Chi;Liu Chun;Cui Xilin CN110028496, 2019, A Location in patent:Paragraph 0056; 0059; 0069
84348-37-8
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75-65-0
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166410-05-5
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1634-04-4
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84348-37-8
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$5.00/250mg
166410-05-5
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$55.00/1g
24424-99-5
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$13.50/25G
166410-05-5
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51-35-4
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$6.00/5g
166410-05-5
158 suppliers
$55.00/1g