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ChemicalBook CAS DataBase List Benzyl formate
104-57-4

Benzyl formate synthesis

13synthesis methods
By heating a mixture of formic/acetic anhydride and benzyl alcohol to 50°C; by passing a mixture of formic acid and excess benzyl alcohol over a catalyst (ThO2 or TiO2) at high temperature.
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Yield:104-57-4 98%

Reaction Conditions:

with tribromo-isocyanuric acid in neat (no solvent) at 20; for 0.0833333 h;

Steps:

Formylation of benzyl alcohol using formic acidcatalyzed by tribromoisocyanuric acid
To a mixture of the benzyl alcohol (1 mmol)and formic acid (3 mmol); 0.1 g tribromoisocyanuricacid (0.3 mmol) was added. The reaction mixturewas stirred at room temperature for 5 min. Aftercompletion of the reaction (TLC), dichloromethane(10 mL) was added to the reaction mixture andfiltered. The product was extracted with H2O (3×10mL), and the organic layer was dried over anhydrousNa2SO4salt. Evaporation of the solvent underreduced pressure to give the almost pure product.

References:

Hekmatian, Zahra;Khazaei, Ardeshir [Oriental Journal of Chemistry,2015,vol. 31,# 3,p. 1565 - 1570]

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