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884-29-7

Benzenamine, 2-chloro-N-(phenylmethylene)- synthesis

14synthesis methods
-

Yield:884-29-7 91.3%

Reaction Conditions:

with potassium carbonate in 1,4-dioxane at 40; for 1.66667 h;Molecular sieve;

Steps:

14 Example 14:

Add 2-chloroaniline (1.1 mmol), benzyl alcohol (1 mmol), 1,4-dioxane (2 mL), potassium carbonate (1.5 mmol) to a 10 mL reaction tube, add molecular sieve HP-MnAlPO -5, the reaction mixture was reacted at 40°C for 100 min. After the reaction was completed, the target product XIII was isolated by column chromatography with a yield of 91.3%.

References:

CN108084050,2020,B Location in patent:Paragraph 0062-0064