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ChemicalBook CAS DataBase List Atorvastatin Acetonide tert-Butyl Ester
125971-95-1

Atorvastatin Acetonide tert-Butyl Ester synthesis

3synthesis methods
125971-94-0 Synthesis
(4R,6R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate

125971-94-0
345 suppliers
$12.00/1g

-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: 95 percent / H2, ammonia / Molybdenum doped Raney nickel / methanol / 2585.7 Torr
2: 75 percent / pivalic acid / toluene; heptane; tetrahydrofuran / Heating

References:

Baumann;Butler;Deering;Mennen;Millar;Nanninga;Palmer;Roth [Tetrahedron Letters,1992,vol. 33,# 17,p. 2283 - 2284]

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