alpha-Methylimidazo[1,2-a]pyridine-6-methanamine synthesis

3synthesis methods

Product Name:alpha-Methylimidazo[1,2-a]pyridine-6-methanamine
CAS Number:1270475-03-0
Molecular formula:C9H11N3
Molecular Weight:161.2

36052-24-1 Synthesis

36052-24-1
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alpha-Methylimidazo[1,2-a]pyridine-6-methanamine

1270475-03-0
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Yield:-

Steps:

Multi-step reaction with 5 steps
1: water; ethanol / 4 h / Reflux
2: isopropylmagnesium chloride / tetrahydrofuran / 1 h / -20 °C / Inert atmosphere
3: tetrahydrofuran / 0 - 20 °C
4: diphenyl phosphoryl azide; 1,8-diazabicyclo[5.4.0]undec-7-ene / tetrahydrofuran / 0 °C
5: ammonium hydroxide; triphenylphosphine / tetrahydrofuran / 20 °C

References:

Jia, Hong;Dai, Guangxiu;Weng, Jianyang;Zhang, Zhulin;Wang, Qing;Zhou, Feng;Jiao, Longxian;Cui, Yumin;Ren, Yongxin;Fan, Shiming;Zhou, Jinghong;Qing, Weiguo;Gu, Yi;Wang, Jian;Sai, Yang;Su, Weiguo [Journal of Medicinal Chemistry,2014,vol. 57,# 18,p. 7577 - 7589]

136117-69-6 Synthesis

METHYL IMIDAZO[1,2-A]PYRIDINE-6-CARBOXYLATE

136117-69-6
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$32.00/500mg

1270475-03-0
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References

N-methoxy-N-methylimidazo[1,2-a]pyridine-6-carboxamide

1313726-20-3
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1270475-03-0
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References