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10302-94-0

ALPHA-CHLOROFUMARICACIDDIETHYLESTER synthesis

8synthesis methods
-

Yield:-

Reaction Conditions:

Stage #1: diethyl Fumaratewith chlorine in dichloromethane;
Stage #2: with sodium ethanolate in ethanol;

References:

Webb, Thomas R.;Moran, Terry;Huang, Charles Q.;McCarthy, James R.;Grigoriadis, Dimitri E.;Chen, Chen [Bioorganic and Medicinal Chemistry Letters,2004,vol. 14,# 15,p. 3869 - 3873]