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ChemicalBook CAS DataBase List 9,9-Diethylfluorene-2-boronicacid
400607-30-9

9,9-Diethylfluorene-2-boronicacid synthesis

3synthesis methods
287493-15-6 Synthesis
2-Bromo-9,9-diethylfluorene

287493-15-6
131 suppliers
$22.00/250mg

9,9-Diethylfluorene-2-boronicacid

400607-30-9
21 suppliers
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Yield:400607-30-9 71%

Reaction Conditions:

Stage #1: 2-bromo-9,9-diethyl-9H-fluorenewith n-butyllithium in tetrahydrofuran;hexane at -78; for 1 h;
Stage #2: with Triisopropyl borate in tetrahydrofuran;hexane at -78 - 20;
Stage #3: with hydrogenchloride in water; pH=2 - 3;cooling;

References:

Yang, Jye-Shane;Lee, Yar-Ru;Yan, Jyu-Lun;Lu, Ming-Chun [Organic Letters,2006,vol. 8,# 25,p. 5813 - 5816]

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