5-METHOXY-1H-INDAZOLE-3-CARBOXYLIC ACID ETHYL ESTER synthesis
- Product Name:5-METHOXY-1H-INDAZOLE-3-CARBOXYLIC ACID ETHYL ESTER
- CAS Number:865887-16-7
- Molecular formula:C11H12N2O3
- Molecular Weight:220.22
![2H-Indazole-3-carboxylic acid, 5-methoxy-2-[[2-(trimethylsilyl)ethoxy]methyl]-, ethyl ester](/CAS/20210305/GIF/1210745-27-9.gif)
1210745-27-9
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865887-16-7
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Yield:865887-16-7 79%
Reaction Conditions:
Stage #1: ethyl 5-methoxy-2-{[(2-trimethylsilyl)ethoxy]methyl}-2H-indazole-3-carboxylatewith hydrogenchloride;water in ethanol at 20;
Stage #2: with sodium carbonate in ethanol;water;
References:
Vernekar, Sanjeev Kumar V.;Hallaq, Hasan Y.;Clarkson, Guy;Thompson, Andrew J.;Silvestr, Linda;Lummis, Sarah C. R.;Lochner, Martin [Journal of Medicinal Chemistry,2010,vol. 53,# 5,p. 2324 - 2328] Location in patent:supporting information; experimental part
64-17-5
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90417-53-1
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$54.00/100mg
865887-16-7
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39755-95-8
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$8.00/1g
865887-16-7
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