2-(4-Fluorophenyl)-1H-benzimidazole-5-carboxylic acid synthesis

1synthesis methods

Product Name:2-(4-Fluorophenyl)-1H-benzimidazole-5-carboxylic acid
CAS Number:850705-30-5
Molecular formula:C14H9FN2O2
Molecular Weight:256.23

459-57-4 Synthesis

459-57-4
596 suppliers
$6.00/25g

2-(4-Fluorophenyl)-1H-benzimidazole-5-carboxylic acid

850705-30-5
17 suppliers
$18.00/250mg

Yield:-

Steps:

Multi-step reaction with 2 steps
1: disodium metabisulfite; lithium hydroxide monohydrate / ethanol / 0.5 h / 20 °C
2: N,N-dimethyl-formamide / 0.05 h / 240 °C / 7500.75 Torr

References:

Polat, Bilge Uzun;?evik, Ulviye Acar;Dikmen, Miri?;?zkay, Yusuf [Pharmaceutical Chemistry Journal,2022,vol. 56,# 4,p. 451 - 455]

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2-(4-fluorophenyl)-1H-benzimidazole