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ChemicalBook CAS DataBase List 7-(TRIFLUOROMETHYL)-1-TETRALONE
54752-50-0

7-(TRIFLUOROMETHYL)-1-TETRALONE synthesis

2synthesis methods
145485-43-4 Synthesis
4-(3-TrifluoroMethyl-phenyl)-butyric acid

145485-43-4
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Yield:-

Steps:

34.D Step D:
Step D: 7-Trifluoromethyl-1-tetralone Prepared from 4-(3-trifluoromethylphenyl)butanoic acid by the procedure described in Example 32, Step A. 1 H NMR (200 MHz, CDCl3): 2.16 (m,2H), 2.69 (t,6 Hz,2H), 3.01 (t,6 Hz,2H), 7.5 (m,2H), 8.12 (d,8 Hz,1H). EI-MS: calculated for C11 H9 F3 O 214; found 214 (M+,40%).

References:

Merck & Co., Inc. US5206235, 1993, A

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