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ChemicalBook CAS DataBase List 6-BROMO-4-HYDROXY-2-(TRIFLUOROMETHYL)QUINOLINE
1701-22-0

6-BROMO-4-HYDROXY-2-(TRIFLUOROMETHYL)QUINOLINE synthesis

1synthesis methods
-

Yield:-

Reaction Conditions:

Stage #1:ethyl 4,4,4-trifluoroacetoacetate;4-bromo-aniline with magnesium sulfate;acetic acid in ethanol at 90; for 16 h;
Stage #2: with dowtherm A at 230 - 250; for 0.5 h;

References:

Yang, Guan-Zhou;Zhu, Jia-Kai;Yin, Xiao-Dan;Yan, Yin-Fang;Wang, Yu-Ling;Shang, Xiao-Fei;Liu, Ying-Qian;Zhao, Zhong-Min;Peng, Jing-Wen;Liu, Hua [Journal of Agricultural and Food Chemistry,2019,vol. 67,# 41,p. 11340 - 11353]

FullText

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