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ChemicalBook CAS DataBase List 6-BROMO-4-CHLORO-3-FORMYLCOUMARIN 97
51069-90-0

6-BROMO-4-CHLORO-3-FORMYLCOUMARIN 97 synthesis

3synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 4 steps
1: pyridine / dichloromethane / 5 h / 0 - 20 °C
2: aluminum (III) chloride / 5 h / 0 - 120 °C
3: sodium hydride / 4 h / 0 - 110 °C
4: trichlorophosphate / 0 - 60 °C

References:

Bhimapaka, China Raju;Karri, Shailaja;Kuncha, Madhusudana;Kurma, Siva Hariprasad;Sistla, Ramakrishna [Bioorganic and medicinal chemistry letters,2020,vol. 30,# 16]

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