天堂网亚洲,天天操天天搞,91视频高清,菠萝蜜视频在线观看入口,美女视频性感美女视频,95丝袜美女视频国产,超高清美女视频图片

Welcome to chemicalbook!
Chinese English Japanese Germany Korea
400-158-6606
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

ChemicalBook CAS DataBase List 1-Piperazinecarboxylicacid,4-methyl-,ethylester(6CI,9CI)
59325-11-0

1-Piperazinecarboxylicacid,4-methyl-,ethylester(6CI,9CI) synthesis

3synthesis methods
-

Yield:59325-11-0 65.5%

Reaction Conditions:

with sodium cyanide in dichloromethane at 0 - 20; for 2 h;

Steps:

2 Example 2: The preparation method of ethyl 4-methylpiperazine-1-carboxylate

1. Add 10 g of 4-methylpiperazine-1-formyl chloride hydrochloride and 50 ml of dichloromethane into the reaction flask, then add 5 ml of ethanol, and then cool down to 0-5 °C, add 2 g of sodium cyanide in batches, add After completion, return to room temperature and stir for 2h.2. After adding 50 ml of water to the system, adjust the pH to 6.4 with 4M dilute hydrochloric acid, stir at room temperature, separate the liquid, and keep the water phase.3. The aqueous phase was adjusted to pH 9 with an aqueous sodium carbonate solution, extracted twice with 50 ml of dichloromethane, the organic phases were combined and dried, and the organic phase was spin-dried at 40°C in vacuo to obtain 4-methylpiperazine-1-ethyl formate 5.7 g as a light yellow transparent oil.Yield 65.5%, purity 98.8%.

References:

CN114763342,2022,A Location in patent:Paragraph 0056-0061

1-Piperazinecarboxylicacid,4-methyl-,ethylester(6CI,9CI) Related Search: