5-CHLOROTHIOPHENE-2-CARBONYL CHLORIDE synthesis
- Product Name:5-CHLOROTHIOPHENE-2-CARBONYL CHLORIDE
- CAS Number:42518-98-9
- Molecular formula:C5H2Cl2OS
- Molecular Weight:181.04
24065-33-6
757 suppliers
$6.00/5g
42518-98-9
287 suppliers
$8.00/1g
Yield:42518-98-9 100%
Reaction Conditions:
with thionyl chloride;N,N-dimethyl-formamide in dichloromethane for 16 h;Heating / reflux;
Steps:
12.b (b)
32.0 g (0.20 mmol) 5-chloro-thiophene-2-carboxylic acid are 150 ml dichloromethane refluxed for 16 h with stirring with 100 ml of thionyl chloride and 250 μl DMF. The reaction mixture is evaporated down i. vac., the residue in each case is mixed 5 times with toluene and twice with dichloromethane and evaporated down completely. The residue is further reacted directly without any further purification.Yield: quant.C5H2Cl2OS (181.04)
References:
Dahmann, Georg;Gerlach, Kai;Pfau, Roland;Priepke, Henning;Wienen, Wolfgang;Schuler-Metz, Annette;Nar, Herbert US2008/51578, 2008, A1 Location in patent:Page/Page column 39
6310-09-4
199 suppliers
$9.00/5g
42518-98-9
287 suppliers
$8.00/1g
96-43-5
355 suppliers
$5.00/25g
34718-47-3
9 suppliers
$173.00/10g
42518-98-9
287 suppliers
$8.00/1g
