5-Chloroindole synthesis
- Product Name:5-Chloroindole
- CAS Number:17422-32-1
- Molecular formula:C8H6ClN
- Molecular Weight:151.59
129822-48-6
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17422-32-1
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Yield:17422-32-1 98%
Reaction Conditions:
with 2,2,2-trifluoroethanol at 150; for 1 h;Product distribution / selectivity;Microwave irradiation;
Steps:
2
EXAMPLE 2; Following the procedure set forth in Example 1 (A) above, indole derivatives were deprotected using TFE or HFIP in a microwave reactor at 150° C. as set forth in Table 1 below.
References:
Roch Palo Alto LLC US2009/203910, 2009, A1 Location in patent:Page/Page column 2-3
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17422-32-1
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10075-50-0
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17422-32-1
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25658-80-4
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17422-32-1
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