5-Bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidine synthesis

1synthesis methods

Product Name:5-Bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidine
CAS Number:22276-95-5
Molecular formula:C6H3BrClN3
Molecular Weight:232.47

4-chloro-7H-pyrrolo[2,3-d]pyrimidine (30 g/0.02 mol) was dissolved in 75 mL of chloroform, followed by added 3.5 g (0.02 mol) of N-bromosuccinamide. The resulting mixture was refluxed for 1 h. After cooling to room temperature, the precipitate was removed by filtration and dried under reduced pressure to afford 5-Bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidine.

5-Bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidine

3680-69-1 Synthesis

3680-69-1
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$6.00/1g

22276-95-5
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$8.00/1g

Yield:22276-95-5 99%

Reaction Conditions:

with N-Bromosuccinimide in acetonitrile at 100; for 0.166667 h;microwave irradiation;

References:

Wu, Tom Y. H.;Schultz, Peter G.;Ding, Sheng [Organic Letters,2003,vol. 5,# 20,p. 3587 - 3590]

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