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ChemicalBook CAS DataBase List 5-Aminouracil
932-52-5

5-Aminouracil synthesis

6synthesis methods
-

Yield:932-52-5 92%

Reaction Conditions:

with Sodium hydrogenocarbonate;Na2S2O3 in lithium hydroxide monohydrate at 75; for 4 h;Reagent/catalyst;Temperature;

Steps:

11.1; 12.1; 13.1 step 1:

50 g of Na 2S 2 O 4 were added in portions to a saturated aqueous solution of 10 g of 5-nitrouracil and 20 g of sodium bicarbonate and stirred at 75° C. for 4 hours. The resulting white precipitate was filtered, washed with water and dried to obtain 7.4 g of 5-aminouracil (yield: 92%).

References:

WO2022/96015,2022,A1 Location in patent:Page/Page column 24-26

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