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ChemicalBook CAS DataBase List 5-Aminosulfonyl-2-Ox-Indole
175075-24-8

5-Aminosulfonyl-2-Ox-Indole synthesis

4synthesis methods
-

Yield:175075-24-8 21%

Reaction Conditions:

with ammonia in methanol at 20;

Steps:



A suspension of 2.1 g (9 mmol) of 5-chlorosulfonyl-2-oxindole in 10 mL (20 mmol) of 2 M ammonia in methanol was stirred at room temperature overnight. The precipitate was collected by vacuum filtration, washed with water and dried under vacuum to give 0.4 g (21% yield) of the title compound.

References:

US2004/186160,2004,A1 Location in patent:Page/Page column 21

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