ChemicalBook CAS DataBase List 4-(Methylphenyl)sulfonylacetonitrile

4-(Methylphenyl)sulfonylacetonitrile synthesis

5synthesis methods

Product Name:4-(Methylphenyl)sulfonylacetonitrile
CAS Number:5697-44-9
Molecular formula:C9H9NO2S
Molecular Weight:195.24

1576-35-8 Synthesis

1576-35-8
451 suppliers
$10.00/1g

75-05-8 Synthesis

75-05-8
988 suppliers
$10.00/10g

5697-44-9
127 suppliers
$15.00/1g

Yield:5697-44-9 86%

Reaction Conditions:

with dipotassium peroxodisulfate at 80; for 5 h;Temperature;

Steps:

2
In a clean and dry 100 ml round bottom flask, 10 mmol of p-toluenesulfonylhydrazine, 30 mmol of potassium persulfate, 25 ml of acetonitrile were successively added, followed by further reaction at 80 ° C for 5 hours.After the reaction, the reaction solvent was directly dried by a rotary evaporator, and the residue was recrystallized from petroleum ether and dichloromethane.A yellow solid was obtained with a yield of about 86%.

References:

Xinyang Normal University;Tan Meirong CN108558717, 2018, A Location in patent:Paragraph 0033; 0035-0036; 0039

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824-79-3 Synthesis