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ChemicalBook CAS DataBase List 4-(Isopropylamino)butanol
42042-71-7

4-(Isopropylamino)butanol synthesis

3synthesis methods
-

Yield:42042-71-7 100%

Reaction Conditions:

with palladium 10% on activated carbon;hydrogen in ethanol; under 7500.75 Torr;

Steps:

2 Example 2: Preparation of 4-(isopropylamino)-1-butanol (III)

200 gm of 4-amino-1-butanol (II) was dissolved in a mixed solvent of 400 ml of acetone and 1000 ml of ethanol and, after adding 20 gm of 10% Pd/C, hydrogenation was carried out under the pressure of 10 kg for 4-5 hours. The reaction solution was filtered to remove the catalyst and the filtrate obtained was concentrated to obtain desired compound in quantitative yield, as a colorless oily substance

References:

WO2017/60827,2017,A1 Location in patent:Page/Page column 11

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