ChemicalBook CAS DataBase List 4-Chlorobenzenesulfonyl chloride

4-Chlorobenzenesulfonyl chloride synthesis

11synthesis methods

Product Name:4-Chlorobenzenesulfonyl chloride
CAS Number:98-60-2
Molecular formula:C6H4Cl2O2S
Molecular Weight:211.07

4-Chlorobenzenesulfonyl chloride is manufactured by mixing 4-chlorobenzene and chlorosulfuric acid at 35 ℃, heating for two hours at 80 ℃, and discharging the contents of the reactor into ice water; yield 81% of theory, together with a small amount of bis(4-chlorophenyl) sulfone.

108-90-7
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$10.00/25G

98-60-2
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$5.00/5g

Yield:98-60-2 87.1%

Reaction Conditions:

with chlorosulfonic acid in dichloromethane at 5 - 20; for 12 h;

Steps:

1.d Step d Preparation of 4-chlorobenzenesulfonyl chloride
(20 g, 0.24 mol) was dissolved in methylene chloride, and the temperature was below 5 ° C. Chlorosulfonic acid (55.6 g, 0.48 mol) was slowly added dropwise. Drop at room temperature for 12 h. The reaction solution was slowly poured into 200 mL of ice water, the dichloromethane layer was separated, dried over anhydrous sodium sulfate and evaporated to dryness to give 37.3 g of a brown oil, yield 87.1%.

References:

Jiangxi Science and Technology Normal University;Zheng Pengwu;Zhu Wufu;Wu Chunjiang;Xu Shan;Sun Chengyu;Chen Chen;Chen Zhichao;Xu Mengze CN104496896, 2017, B Location in patent:Page/Page column 0095; 0096

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