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ChemicalBook CAS DataBase List 4-Bromo-2-nitrobenzaldehyde
5551-12-2

4-Bromo-2-nitrobenzaldehyde synthesis

11synthesis methods
22996-19-6 Synthesis
4-Bromo-2-nitrobenzyl alcohol

22996-19-6
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Yield:5551-12-2 78%

Reaction Conditions:

with manganese(IV) oxide in dichloromethane at 20; for 12 h;

Steps:

25.2

Step 2. 4-Bromo-2-nitrobenzaldehydeManganese (IV) oxide (4eq) was added to a 0.18M solution of (4-bromo-2-nitrophenyl)methanol in dichloromethane. The suspension was stirred at ambient temperature under Argon for 12 h. The reaction mixture was filtered through celite and filter cake was washed with dichloromethane. The combined filtrate was concentrated to give brown color solid in 78% yield.

References:

WO2007/117607,2007,A2 Location in patent:Page/Page column 333

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