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92367-45-8

4-(3-Methylphenyl)but-1-ene synthesis

10synthesis methods
-

Yield:92367-45-8 248 mg

Reaction Conditions:

Stage #1: Methyltriphenylphosphonium bromidewith n-butyllithium in tetrahydrofuran;hexane at 0; for 0.5 h;Inert atmosphere;
Stage #2: 3-(3-methylphenyl)propanal in tetrahydrofuran;hexane at -78 - 20;Inert atmosphere;Wittig Olefination;

References:

Nouaille, Augustin;Pannecoucke, Xavier;Poisson, Thomas;Couve-Bonnaire, Samuel [Advanced Synthesis and Catalysis,2021,vol. 363,# 8,p. 2140 - 2147] Location in patent:supporting information

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