4-(1-PIPERAZINYL)-3-TRIFLUOROMETHYLBENZENAMINE synthesis
- Product Name:4-(1-PIPERAZINYL)-3-TRIFLUOROMETHYLBENZENAMINE
- CAS Number:319474-60-7
- Molecular formula:C11H14F3N3
- Molecular Weight:245.24
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Yield:-
Steps:
Multi-step reaction with 2 steps
1: caesium carbonate / dimethyl sulfoxide / 120 °C
2: palladium 10% on activated carbon; hydrogen / methanol / 2 h
References:
FORMA THERAPEUTICS, INC.;GUERIN, David Joseph;BAIR, Kenneth W.;CARAVELLA, Justin A.;IOANNIDIS, Stephanos;LANCIA JR., David R.;LI, Hongbin;MISCHKE, Steven;NG, Pui Yee;RICHARD, David;SCHILLER, Shawn E. R.;SHELEKHIN, Tatiana;WANG, Zhongguo WO2017/139778, 2017, A1