3-Pyridinepropionic acid synthesis
- Product Name:3-Pyridinepropionic acid
- CAS Number:3724-19-4
- Molecular formula:C8H9NO2
- Molecular Weight:151.16
1126-74-5
165 suppliers
$6.00/1g
3724-19-4
119 suppliers
$14.14/250mgs:
Yield: 100%
Reaction Conditions:
with hydrogen;palladium 10% on activated carbon in methanol;ethanol
Steps:
2.1
(1) A mixture of 3-(pyridin-3-yl)propenoic acid (10.0g, 67mmol), 10% palladium-activated carbon (1g), methanol (100mL) and ethanol (100mL) was stirred overnight under hydrogen atmosphere. The resultant reaction mixture was filtered, evaporated, and dried to give 3-(pyridin-3-yl)propionic acid (10.2g, quantitative). 1H NMR(DMSO-d6) δ:2.52(2H, m), 2.81(2H, t, J=7.6Hz), 7.27-7.31(1H, app-dd, J=4.6Hz, 7.9Hz), 7.63-7.67(1H, app-dt, J=7.9H, 1.7Hz), 8.38-8.40(1H, app-dd, J=1.7Hz, 4.6Hz), 8.44-8.45(1H, app-d, J=1.7Hz)
References:
Grelan Pharmaceutical Co., Ltd. EP1559716, 2005, A1 Location in patent:Page/Page column 20
2859-67-8
118 suppliers
$10.00/250mg
3724-19-4
119 suppliers
$14.14/250mgs:
626-55-1
565 suppliers
$5.00/5 / G
3984-22-3
65 suppliers
$123.00/5ml
3724-19-4
119 suppliers
$14.14/250mgs:
2859-67-8
118 suppliers
$10.00/250mg
7440-44-0
308 suppliers
$12.00/25g
3724-19-4
119 suppliers
$14.14/250mgs:
1121-55-7
132 suppliers
$122.00/1g
201230-82-2
1 suppliers
inquiry
3724-19-4
119 suppliers
$14.14/250mgs:
90005-62-2
25 suppliers
$265.00/100mg