3-CHLORO-2,6-DIMETHOXYBENZOIC ACID, 97 synthesis
- Product Name:3-CHLORO-2,6-DIMETHOXYBENZOIC ACID, 97
- CAS Number:36335-47-4
- Molecular formula:C9H9ClO4
- Molecular Weight:216.62
1466-76-8
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$5.00/25mg
36335-47-4
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$33.00/250mg
Yield:36335-47-4 80%
Reaction Conditions:
with N-chloro-succinimide;2,2,6,6-tetramethylpiperidin-1-oxoammonium trifluoromethanesulfonate in chloroform at 25; for 12 h;Schlenk technique;Reagent/catalyst;
Steps:
28.a-28.b
b) Take a 25mL Schlenk reaction tube and add 91.1mg of 2,6-dimethoxybenzoic acid, 79.8mg of N-chlorosuccinimide, 30.1mg of [TEMPO][OTf], 2mL of chloroform, at 25 Stir for 12 hours.After the reaction, the solvent was removed by rotary evaporation and column chromatography was separated to obtain 86.6 mg of 3-chloro-2,6-dimethoxybenzoic acid with a yield of 80%.
References:
CN112573978,2021,A Location in patent:Paragraph 0197-0201
2040-04-2
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36335-47-4
32 suppliers
$33.00/250mg