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ChemicalBook CAS DataBase List 3-Amino-4,6-dimethylpyridine
1193-71-1

3-Amino-4,6-dimethylpyridine synthesis

4synthesis methods
-

Yield:-

Reaction Conditions:

with methanol;palladium on activated charcoal;hydrogen at 20; for 48 h;

Steps:

B Step B. 4, 6-dimethylpyridin-3-amine

To a 20-L round-bottom flask was added a solution of 2,4-dimethyl-5-nitropyridine (624 g, 4101.20 mmol, 1 equiv) in MeOH (8 L) and Pd/C (62.4 g, 0.143 equiv). To this solution, Tk (g) was introduced. The resulting solution was stirred for 48 h at room temperature. The solids were filtered out and the filtrate was concentrated to provide the title compound.

References:

WO2021/202254,2021,A1 Location in patent:Page/Page column 26

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