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ChemicalBook CAS DataBase List (2S,6R)-2,6-dimethylpiperidin-4-one
13200-35-6

(2S,6R)-2,6-dimethylpiperidin-4-one synthesis

2synthesis methods
198211-15-3 Synthesis
RZABKAGQMPNUFJ-TXEJJXNPSA-N

198211-15-3
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Yield: 91.3%

Reaction Conditions:

with hydrogen;palladium(II) hydroxide in methanol for 10 h;

Steps:

1.2 2. Preparation of (2R,6S)-2,6-dimethylpiperidin-4-one
(2R,6S)-1-Benzyl-2,6-dimethylpiperidin-4-one (2 g, 9.2 mol)And 20% palladium hydroxide (2g) was added to methanol (30mL), and reacted under a hydrogen atmosphere for 10h.Filtered and concentrated to give the title compound(1.07 g, yield: 91.3%).

References:

Hainan Xuanzhu Pharmaceutical Technology Co., Ltd.;Shi Chengkong;Chen Bo CN109320509, 2019, A Location in patent:Paragraph 0160; 0165-0167

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