Methacrylic acid 8-hydroxy-3,6-dioxaoctane-1-yl ester synthesis
- Product Name:Methacrylic acid 8-hydroxy-3,6-dioxaoctane-1-yl ester
- CAS Number:2351-42-0
- Molecular formula:C10H18O5
- Molecular Weight:218.25
Yield:2351-42-0 87.2%
Reaction Conditions:
with triethylamine in dichloromethane at 20; for 12 h;Cooling with ice;
Steps:
2
Compound 1 (6.0g, 0.04mol), TEA (8.08g, 0.08mol) were dissolved in 10mL of dichloromethane, under ice-water bath, 10mL of methacrylic acid chloride (2.08g, 0.08mol) was slowly added dropwise. The methyl chloride solution was dripped and reacted at room temperature for 12 hours.The reaction solution was washed with water, extracted with dichloromethane, and dried over anhydrous sodium sulfate. After column separation, 3.8 g of compound 2 was obtained with a yield of 87.2%.
References:
CN113577255,2021,A Location in patent:Paragraph 0057-0059
920-46-7
328 suppliers
$20.00/1g
112-27-6
759 suppliers
$6.00/100g
109-16-0
306 suppliers
$10.00/25g
2351-42-0
6 suppliers
inquiry
79-41-4
500 suppliers
$14.00/5g
112-27-6
759 suppliers
$6.00/100g
109-16-0
306 suppliers
$10.00/25g
2351-42-0
6 suppliers
inquiry
107-21-1
1334 suppliers
$10.00/25g
111-46-6
1078 suppliers
$5.00/25g