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ChemicalBook CAS DataBase List 5-METHYL-3-[3-[3-[4-[2-(2,2,2-TRIFLUOROETHOXY)PHENYL]-1-PIPERAZINYL]PROPYL]-2,4-(1H,3H)-PYRIMIDINEDIONE] HYDROCHLORIDE
232953-52-5

5-METHYL-3-[3-[3-[4-[2-(2,2,2-TRIFLUOROETHOXY)PHENYL]-1-PIPERAZINYL]PROPYL]-2,4-(1H,3H)-PYRIMIDINEDIONE] HYDROCHLORIDE synthesis

2synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 3 steps
1: K2CO3 / dimethylformamide
2: K2CO3; NaI / acetonitrile / Heating
3: HCO2NH4 / Pd/C / methanol / Heating

References:

Lopez;Arias;Chan;Clarke;Elworthy;Ford;Guzman;Jaime-Figueroa;Jasper;Morgans Jr.;Padilla;Perez-Medrano;Quintero;Romero;Sandoval;Smith;Williams;Blue [Bioorganic and Medicinal Chemistry Letters,2003,vol. 13,# 11,p. 1873 - 1878]

5-METHYL-3-[3-[3-[4-[2-(2,2,2-TRIFLUOROETHOXY)PHENYL]-1-PIPERAZINYL]PROPYL]-2,4-(1H,3H)-PYRIMIDINEDIONE] HYDROCHLORIDE Related Search: