ChemicalBook CAS DataBase List 2-PROPIONYLFURAN

2-PROPIONYLFURAN synthesis

11synthesis methods

Product Name:2-PROPIONYLFURAN
CAS Number:3194-15-8
Molecular formula:C7H8O2
Molecular Weight:124.14

534-22-5 Synthesis

534-22-5
295 suppliers
$10.00/5mL

541-88-8 Synthesis

541-88-8
159 suppliers
$10.00/5g

3194-15-8
60 suppliers
$19.00/250mg

Yield:3194-15-8 42.8%

Reaction Conditions:

with propionic acid in toluene

Steps:

33 EXAMPLE 33
EXAMPLE 33 In 50 ml of toluene were dissolved 3.7 g (0.05 mole) of propionic acid and 10.26 g (0.06 mole) of monochloroacetic anhydride. To the resulting solution were added 5.36 g (0.065 mole) of 2-methylfuran and 0.71 g of boron trifluoride-diethyl ether complex and the resulting mixture was then stirred at 50° C. for 7 hours. After completion of the reaction, the reaction solution was cooled and washed successively with 5% aqueous sodium carbonate solution and water. The organic layer was concentrated under reduced pressure and the resulting concentrated residue was then purified by silica gel-filled column chromatography to obtain 2.96 g of 2-propionylfuran. Yield: 42.8% n_D²⁵: 1.5078

References:

Sumitomo Chemical Company, Limited US4812585, 1989, A

FullText

110-00-9 Synthesis