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51491-68-0

2-Phenylacryloyl chloride synthesis

7synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 3 steps
1: potassium carbonate; tetra-(n-butyl)ammonium iodide / toluene / 12 h / 50 °C
2: sodium hydroxide / 2 h / Reflux
3: N,N-dimethyl-formamide; oxalyl dichloride / dichloromethane / 20 °C / Inert atmosphere

References:

Kong, Wangqing;Wang, Qian;Zhu, Jieping [Angewandte Chemie - International Edition,2017,vol. 56,# 14,p. 3987 - 3991][Angew. Chem.,2017,vol. 129,# 14,p. 4045 - 4049]