2-CHLORO-N-(2,3-DIMETHYL-PHENYL)-ACETAMIDE synthesis
- Product Name:2-CHLORO-N-(2,3-DIMETHYL-PHENYL)-ACETAMIDE
- CAS Number:2564-07-0
- Molecular formula:C10H12ClNO
- Molecular Weight:197.66
Yield:2564-07-0 96%
Reaction Conditions:
with sodium hydroxide in dichloromethane;water; for 18 h;
Steps:
17A EXAMPLE 17 ; 2-[4-(3-cyano-2-pyridinyl)-1-piperazinyl]-N-(2.3-dimethylphenyl)acetamide ; EXAMPLE 17A ; 2-chloro-N-(2,3-dimethylphenyl)acetamide
The procedure described in Example 16A was followed, substituting 2,3-dimethylaniline for 3,5-dimethylaniline to provide the title compound (96% yield) as a white solid. 1H NMR (300 MHz, DMSO-d6) ? 2.07 (s, 3H), 2.24 (s, 3H), 4.28 (s, 2H), 7.07 (m, 3H), 9.70 (br s, 1H); MS (DCI/NH3) m/e 198 (M+H)+.
References:
US2003/232836,2003,A1 Location in patent:Page 44
87-59-2
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