ChemicalBook CAS DataBase List 2-Chloro-1,3-dimethylimidazolidinium chloride

2-Chloro-1,3-dimethylimidazolidinium chloride synthesis

5synthesis methods

Product Name:2-Chloro-1,3-dimethylimidazolidinium chloride
CAS Number:37091-73-9
Molecular formula:C5H10Cl2N2
Molecular Weight:169.05

80-73-9 Synthesis

80-73-9
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2-Chloro-1,3-dimethylimidazolidinium chloride

37091-73-9
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Yield:37091-73-9 96.6%

Reaction Conditions:

with phosgene in tetrachloromethane at 5 - 50; for 5.5 h;

Steps:

preparation of chloro-1,3-dimethyl-2-chloroimidazoline
For 1000 ml three port in the reaction bottle, by adding 1,3-dimethyl-2-imidazolidinone (34.2 g, 0.3 mol), carbon tetrachloride (400 ml), stirring slowly dropwise solid phosgene carbon tetrachloride solution (containing solid phosgene 30 g, 0.1 mole, carbon tetrachloride 100 ml), the reaction mixture is kept below 5 °C, violent mixing 0.5 hours, the reaction at room temperature 1 hour, heating to 50 °C, maintain 4 hours. To be the reaction product is cooled to room temperature, filter, a small amount of carbon tetrachloride washing, get a pure white crystalline product chloropivaloyl 1,3-dimethyl-2-chlorotrifluoromethylbenzene imidazoline 49 g, yield of 96.6%,

References:

Beijing Chengyu Pharmaceutical Co., Ltd.;Song, Ye;Wang, Daolin;Wang, Yuping CN105367478, 2016, A Location in patent:Paragraph 0021; 0027; 0028

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80-73-9 Synthesis

80-73-9
567 suppliers
$8.00/25g