ChemicalBook CAS DataBase List 2-broMo-4,4'-di-tert-butylbiphenyl

2-broMo-4,4'-di-tert-butylbiphenyl synthesis

5synthesis methods

Product Name:2-broMo-4,4'-di-tert-butylbiphenyl
CAS Number:70728-89-1
Molecular formula:C20H25Br
Molecular Weight:345.32

1625-91-8 Synthesis

1625-91-8
175 suppliers
$10.00/5g

70728-89-1
57 suppliers
$11.00/5g

Yield:70728-89-1 98.6%

Reaction Conditions:

with bromine;iodine in dichloromethane at 5 - 20; for 2 h;

Steps:

1

EXAMPLE 1 1 g of 4,4'-di-tert-butylbiphenyl were dissolved in 10 g of dichloromethane, and 30 mg of iodine were added. The mixture was then cooled to 5° C. Over a period of 1 h, 650 mg of bromine were added. The mixture was then stirred at room temperature for 1 h. For work-up, 3 ml of a 10% strength solution of NaHSO₃ were added, the phases were separated and the organic phase was washed until neutral, dried and concentrated using a rotary evaporator. This gave 1.28 g of 2-bromo-4,4'-di-tert-butylbiphenyl (98.6% of theory).

References:

US2007/293708,2007,A1 Location in patent:Page/Page column 1

860435-39-8 Synthesis