2,5-Dimethoxynaphthalene synthesis

4synthesis methods

Product Name:2,5-Dimethoxynaphthalene
CAS Number:3900-49-0
Molecular formula:C12H12O2
Molecular Weight:188.22

575-44-0 Synthesis

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3900-49-0
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Yield: 90%

Reaction Conditions:

with potassium carbonate in N,N-dimethyl-formamide at 20; for 2 h;

Steps:

21.1 (1) Synthesis of a Methyl Derivative (Compound 40)
Into a round-bottom flask equipped with a stirring apparatus, 1.6 g (10.0 mmol) of 1,6-dihydroxynaphthalene (Compound 39: produced by Tokyo Chemical Industry Co., Ltd.), and 15 mL of N,N-dimethylformamide (DMF) were added for dissolution, and thrther 14.2 g (100.0 mmol) of methyl iodide (produced by Wako Pure Chemical Industries, Ltd.), and 13.8 g (100.0 mmol) of potassium carbonate (produced by Wako Pure Chemical Industries, Ltd.) were added, and the reaction was carried out at room temperature for 2 hours. Afier completion of the reaction, dichloromethane and water were added, and then an organic layer, obtained by solution separation, was washed with water, and the solvent was removed from the reaction solution by concentration under reduced pressure to obtain 1 .7 g (yield:90%) of a colorless liquid methyl derivative (Compound40).

References:

Wako Pure Chemical Industries, Ltd.;Suzuki, Katsufumi;Tsurumi, Yoshihisa;Kawano, Kei;Imazeki, Shigeaki;Murase, Tetsuji US2017/342031, 2017, A1 Location in patent:Paragraph 0643

575-44-0 Synthesis

575-44-0
357 suppliers
$7.00/10g