2-(4-Methylphenyl)propanoic acid synthesis
- Product Name:2-(4-Methylphenyl)propanoic acid
- CAS Number:938-94-3
- Molecular formula:C10H12O2
- Molecular Weight:164.2
75920-45-5
7 suppliers
inquiry
938-94-3
249 suppliers
$70.00/1g
Yield:938-94-3 92%
Reaction Conditions:
with sodium hydroxide at 100 - 105;
Steps:
1.4 Step 4
Add 14.5 g of compound III to a 250 mL three-necked flask.3 mol/L sodium hydroxide solution 100 g,The reaction is refluxed at 100-105 ° C for 8 - 10 h, the reaction is completed, the temperature is reduced to room temperature, acidified to pH 2.0 - 3.0 with hydrochloric acid, extracted with toluene, the organic phase is washed with water, dried over anhydrous sodium sulfate, filtered and evaporated. , adding n-hexane, crystallization,15 g of the compound 2-(4-methyl)phenylpropionic acid (IV) was obtained as a white solid, yield 92%, HPLC. Purity is 98%
References:
Panjin Ge Linkaimo Technology Co., Ltd.;Gong Ningrui CN109809962, 2019, A Location in patent:Paragraph 0011
124-38-9
129 suppliers
$175.00/23402
159755-12-1
0 suppliers
inquiry
938-94-3
249 suppliers
$70.00/1g
622-97-9
134 suppliers
$10.00/5mL
124-38-9
129 suppliers
$175.00/23402
1505-50-6
152 suppliers
$11.00/1g
938-94-3
249 suppliers
$70.00/1g