2-(4-methylphenyl)propanenitrile synthesis
13synthesis methods
- Product Name:2-(4-methylphenyl)propanenitrile
- CAS Number:75920-45-5
- Molecular formula:C10H11N
- Molecular Weight:145.2
Yield:75920-45-5 100%
Reaction Conditions:
with 3-[bis-(4-methoxy-phenyl)-phosphanyl]-2H-isoquinolin-1-one;N-{6-[bis-(4-methoxy-phenyl)-phosphanyl]-pyridin-2-yl}-2,2-dimethyl-propionamide;bis(1,5-cyclooctadiene)nickel (0) in toluene at 35; for 25 h;Inert atmosphere;regioselective reaction;
References:
De Greef, Michiel;Breit, Bernhard [Angewandte Chemie - International Edition,2009,vol. 48,# 3,p. 551 - 554] Location in patent:supporting information; experimental part