2,4-Dinitrotoluene synthesis
- Product Name:2,4-Dinitrotoluene
- CAS Number:121-14-2
- Molecular formula:C7H6N2O4
- Molecular Weight:182.13
Alternative processes yield mixed isomer products. When toluene is nitrated directly under similar conditions with 2.1 equivalents of nitric acid, the product is a ca. 80 : 20 mixture of 2,4-dinitrotoluene and 2,6-dinitrotoluene [606-20-2]. Nitration of 2-nitrotoluene, which is sometimes present in surplus, gives a ca. 67 : 33 mixture of 2,4- and 2,6-dinitrotoluene.
108-88-3
7 suppliers
$21.80/5 mL
99-99-0
321 suppliers
$5.00/5 g
121-14-2
2 suppliers
$22.39/033s-1.2ml
606-20-2
5 suppliers
$13.00/5g
Yield:121-14-2 85% ，606-20-2 6.3% ，99-99-0 7.9%
Reaction Conditions:
with succinic acid anhydride;nitric acid at 4; for 50 h;Product distribution / selectivity;
Steps:
10
Examples 8 to 11 : Nitration of toluene using solid anhydridesExamples 8 to 1 1 illustrate the effect of the use of various solid acid anhydrides on the double nitration of toluene. In the examples 8 to 1 1 , a mixture of toluene (35 mmol, 3.75 ml), nitric acid (120 mmol, 5.04 ml), anhydride (120 mmol), zeolite Ηβ (Si/AI = 12.5; 2.0 g) and dichloromethane (10 ml) was stirred in a bath set at 50 °C for the stated period of time. The results are shown in Table 2.Table 2: The effect of solid acid anhydride on the nitration of toluene
References:
UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED;SMITH, Keith;EL-HITI, Gamal;ALOTAIBI, Mohammad WO2012/49513, 2012, A1 Location in patent:Page/Page column 10
108-88-3
7 suppliers
$21.80/5 mL
121-14-2
2 suppliers
$22.39/033s-1.2ml
99-99-0
321 suppliers
$5.00/5 g
121-14-2
2 suppliers
$22.39/033s-1.2ml
88-72-2
262 suppliers
$15.00/25g
121-14-2
2 suppliers
$22.39/033s-1.2ml
88-72-2
262 suppliers
$15.00/25g
121-14-2
2 suppliers
$22.39/033s-1.2ml
606-20-2
5 suppliers
$13.00/5g