2,4-DIHYDROXY-3-FORMYLQUINOLINE synthesis
- Product Name:2,4-DIHYDROXY-3-FORMYLQUINOLINE
- CAS Number:529-89-5
- Molecular formula:C10H7NO3
- Molecular Weight:189.17
70254-44-3
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Yield:-
Reaction Conditions:
with aniline
Steps:
C.1 (Synthesis of compound 1 shown in Table 1 by a conventional method)
Comparative Example 1 (Synthesis of compound 1 shown in Table 1 by a conventional method) To 100 ml of ethanol, 2,4-dihydroxy-3-formylquinoline obtained by formylation of 16.1 g of 2,4-dihydroxyquinoline and 9.5 g of aniline were added and the mixture was maintained under reflux for 180 minutes. The mixture was air-cooled with stirring and filtered at room temperature. Then, the resulting cake was washed with ethanol, dried and then recrystallized from dimethylformamide (DMF) to give a pale yellow powder, m.p. 262 to 265°C. The yield was about 55%. The powder was subjected to a spectrum analysis. As a result, an absorption curve which is the same as that of Example 1 was obtained.
References:
EP640591,1995,A1
