1-O-TOLYL-BUTANE-1,3-DIONE synthesis

5synthesis methods

Product Name:1-O-TOLYL-BUTANE-1,3-DIONE
CAS Number:56290-54-1
Molecular formula:C11H12O2
Molecular Weight:176.21

118-93-4
565 suppliers
$10.00/25g

141-78-6 Synthesis

141-78-6
629 suppliers
$22.37/250ml

56290-54-1
28 suppliers
$121.00/0.5g

Yield:56290-54-1 80%

Reaction Conditions:

with sodium hydride at 20;

Steps:

1 Example 1Preparation of 1-(2-hydroxyphenyl)-1,3-butanedione:

1-(2-Hydroxyphenyl)ethanone (2.0 g, 14.7 mmol) was dissolved in 50 mL of ethyl acetate and sodium hydride was obtained(1.6 g, 68 mmol) was slowly added to the solution and allowed to react at room temperature for 10-15 h. After the reaction is finished, the filter is separated into gray-green solidThe solid was then added to about 200 mL of ultrapure water and the pH was adjusted with dilute H2SO4. Extracted with ethyl acetate and dried over anhydrous sodium sulfateDrying, filtration and evaporation of EtOAc Product notPurified for use in the next step.

References:

CN108558859,2018,A Location in patent:Paragraph 0027-0031

141-78-6 Synthesis

141-78-6
629 suppliers
$22.37/250ml