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ChemicalBook CAS DataBase List 1-BROMO-2-NAPHTHOIC ACID
20717-79-7

1-BROMO-2-NAPHTHOIC ACID synthesis

10synthesis methods
-

Yield:20717-79-7 78.6%

Reaction Conditions:

with potassium permanganate in water;acetone; for 5.5 h;Reflux;

Steps:

1.4

4) in a 250 ml round-bottom flask by adding 1.59g1-bromo-2-hydroxy methyl naphthalene and 22 ml acetone, heating to reflux. The 3.67g potassium permanganate dissolved in 8.1 ml water and 55 ml acetone, the add drop after heating thereof in the round-bottom flask, the 30 min, heat to reflux and 5h, the solution becomes brown, stop should be instead instead, filtering, the generated MnO2solid precipitate is filtered, washing with ethyl ether. Concentrated to obtain the product (1-bromo-2-naphthoic acid) 1.32g, the yield is 78.6%.

References:

CN105541605,2016,A Location in patent:Paragraph 0017; 0026; 0035; 0044; 0071; 0080

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