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ChemicalBook CAS DataBase List 1-(7-CARBOXYHEPTYL)IMIDAZOLE
68887-68-3

1-(7-CARBOXYHEPTYL)IMIDAZOLE synthesis

4synthesis methods
17696-11-6 Synthesis
8-Bromooctanoic acid

17696-11-6
312 suppliers
$13.00/1g

-

Yield:-

Steps:

Multi-step reaction with 3 steps
1: dicyclohexyl-carbodiimide; dmap / dichloromethane / 48 h / 20 °C
2: 18-crown-6 ether / N,N-dimethyl-formamide / 4.5 h / 20 °C / Inert atmosphere
3: trifluoroacetic acid; chlorotriisopropylsilane / dichloromethane / 1 h / 20 °C

References:

Olaleye, Tayo O.;Brannigan, James A.;Roberts, Shirley M.;Leatherbarrow, Robin J.;Wilkinson, Anthony J.;Tate, Edward W. [Organic and Biomolecular Chemistry,2014,vol. 12,# 41,p. 8132 - 8137]

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