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ChemicalBook CAS DataBase List 1-(2-HYDROXYPHENYL)PIPERAZINE
1011-17-2

1-(2-HYDROXYPHENYL)PIPERAZINE synthesis

4synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: palladium diacetate; XPhos; sodium t-butanolate / toluene / 90 °C
2: hydrogenchloride / 1,4-dioxane / 20 °C

References:

Siebeneicher, Holger;Bauser, Marcus;Buchmann, Bernd;Heisler, Iring;Müller, Thomas;Neuhaus, Roland;Rehwinkel, Hartmut;Telser, Joachim;Zorn, Ludwig [Bioorganic and Medicinal Chemistry Letters,2016,vol. 26,# 7,p. 1732 - 1737]

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