Tenovin-6
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- $60 - $2293
- Product name: Tenovin-6
- CAS: 1011557-82-6
- MF: C25H34N4O2S
- MW: 454.63
- EINECS:200-256-5
- MDL Number:MFCD11976906
- Synonyms:Tenovin-6;4-TERT-BUTYL-N-(4-(5-(DIMETHYLAMINO)PENTANAMIDO)PHENYLCARBAMOTHIOYL)BENZAMIDE HYDROCHLORIDE;N-[[[4-[[5-(Dimethylamino)-1-oxopentyl]amino]phenyl]amino]thioxomethyl]-4-(1,1-dimethylethyl)benzamide;Benzamide, N-[[[4-[[5-(dimethylamino)-1-oxopentyl]amino]phenyl]amino]thioxomethyl]-4-(1,1-dimethylethyl)-;N-[[[4-[[5-(Dimethylamino)-1-oxopentyl]amino]phenyl]amino]thioxomethyl]-4-(1,1-dimethylethyl)benzamide Tenovin-6;Tenovin-6, >=98%;4-(tert-Butyl)-N-((4-(4-(dimethylamino)butanamido)phenyl)carbAmothioyl)benzamide;Tenovin 6 - Tnv 6
29 prices
Selected condition：
Brand
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Axon Medchem
- Biorbyt Ltd
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Medical Isotopes, Inc.
- TRC
Package
- 1mg
- 2mg
- 5mg
- 10mg
- 25mg
- 50mg
- 10mM(in 1mL DMSO)
- 100mg
- 250mg
- 1g
- 1000mg
- ManufacturerAmbeed
- Product numberA693915
- Product description4-(tert-Butyl)-N-((4-(5-(dimethylamino)pentanamido)phenyl)carbamothioyl)benzamide 98+%
- Packaging5mg
- Price$211
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA693915
- Product description4-(tert-Butyl)-N-((4-(5-(dimethylamino)pentanamido)phenyl)carbamothioyl)benzamide 98+%
- Packaging10mg
- Price$343
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA693915
- Product description4-(tert-Butyl)-N-((4-(5-(dimethylamino)pentanamido)phenyl)carbamothioyl)benzamide 98+%
- Packaging25mg
- Price$569
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0004725
- Product descriptionN-(((4-((5-(DIMETHYLAMINO)-1-OXOPENTYL)AMINO)PHENYL)AMINO)THIOXOMETHYL)-4-(1,1-DIMETHYLETHYL)-BENZAMIDE 95.00%
- Packaging5MG
- Price$501.23
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8302
- Product descriptionTenovin-6
- Packaging1mg
- Price$80
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8302
- Product descriptionTenovin-6
- Packaging5mg
- Price$230
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8302
- Product descriptionTenovin-6
- Packaging10mM(in 1mL DMSO)
- Price$230
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8302
- Product descriptionTenovin-6
- Packaging10mg
- Price$360
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8302
- Product descriptionTenovin-6
- Packaging25mg
- Price$710
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon2249
- Product descriptionTenovin6-Tnv6 99%
- Packaging25mg
- Price$401.5
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb181161
- Product descriptionTenovin-6 >98%
- Packaging100mg
- Price$578
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb181161
- Product descriptionTenovin-6 >98%
- Packaging250mg
- Price$1133.9
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb181161
- Product descriptionTenovin-6 >98%
- Packaging1000mg
- Price$2245.7
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number13086
- Product descriptionTenovin-6 ≥95%
- Packaging25mg
- Price$2293
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number13086
- Product descriptionTenovin-6 ≥95%
- Packaging10mg
- Price$1048
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number13086
- Product descriptionTenovin-6 ≥95%
- Packaging5mg
- Price$590
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Ambeed | A693915 | 4-(tert-Butyl)-N-((4-(5-(dimethylamino)pentanamido)phenyl)carbamothioyl)benzamide 98+% | 5mg | $211 | 2021-12-16 | Buy |
| Ambeed | A693915 | 4-(tert-Butyl)-N-((4-(5-(dimethylamino)pentanamido)phenyl)carbamothioyl)benzamide 98+% | 10mg | $343 | 2021-12-16 | Buy |
| Ambeed | A693915 | 4-(tert-Butyl)-N-((4-(5-(dimethylamino)pentanamido)phenyl)carbamothioyl)benzamide 98+% | 25mg | $569 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0004725 | N-(((4-((5-(DIMETHYLAMINO)-1-OXOPENTYL)AMINO)PHENYL)AMINO)THIOXOMETHYL)-4-(1,1-DIMETHYLETHYL)-BENZAMIDE 95.00% | 5MG | $501.23 | 2021-12-16 | Buy |
| ApexBio Technology | A8302 | Tenovin-6 | 1mg | $80 | 2021-12-16 | Buy |
| ApexBio Technology | A8302 | Tenovin-6 | 5mg | $230 | 2021-12-16 | Buy |
| ApexBio Technology | A8302 | Tenovin-6 | 10mM(in 1mL DMSO) | $230 | 2021-12-16 | Buy |
| ApexBio Technology | A8302 | Tenovin-6 | 10mg | $360 | 2021-12-16 | Buy |
| ApexBio Technology | A8302 | Tenovin-6 | 25mg | $710 | 2021-12-16 | Buy |
| Axon Medchem | Axon2249 | Tenovin6-Tnv6 99% | 25mg | $401.5 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb181161 | Tenovin-6 >98% | 100mg | $578 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb181161 | Tenovin-6 >98% | 250mg | $1133.9 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb181161 | Tenovin-6 >98% | 1000mg | $2245.7 | 2021-12-16 | Buy |
| Cayman Chemical | 13086 | Tenovin-6 ≥95% | 25mg | $2293 | 2021-12-16 | Buy |
| Cayman Chemical | 13086 | Tenovin-6 ≥95% | 10mg | $1048 | 2021-12-16 | Buy |
| Cayman Chemical | 13086 | Tenovin-6 ≥95% | 5mg | $590 | 2021-12-16 | Buy |
Properties
Density :1.171±0.06 g/cm3(Predicted)
storage temp. :Store at -20° C
solubility :≥22.75 mg/mL in DMSO; insoluble in H2O; ≥2.62 mg/mL in EtOH with ultrasonic
form :solid
pka :9.11±0.70(Predicted)
color :White to off-white
storage temp. :Store at -20° C
solubility :≥22.75 mg/mL in DMSO; insoluble in H2O; ≥2.62 mg/mL in EtOH with ultrasonic
form :solid
pka :9.11±0.70(Predicted)
color :White to off-white
Safety Information
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Description
The tumor suppressor function of p53 hinges on its ability to function as a transcription factor. Tenovin-6 is an analog of tenovin-1, a small molecule activator of p53 transcriptional activity. At 10 μM, this compound is slightly more effective than tenovin-1 at elevating p53 activity in MCF-7 cells and reduces growth of ARN8 melanoma xenograft tumors in SCID mice at a dose of 50 mg/kg. Tenovin-6 inhibits the protein deacetylase activities of purified human SIRT1, SIRT2, and SIRT3 in vitro with IC50 values of 21, 10, and 67 μM, respectively.Related product price
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