SPARSOMYCIN
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- $189 - $755
- Product name: SPARSOMYCIN
- CAS: 1404-64-4
- MF: C13H19N3O5S2
- MW: 361.44
- EINECS:
- MDL Number:MFCD01684112
- Synonyms:Aids-012106;B 120121L19;nsc59729 ;sparsomycin ;Sparsomycin from Streptomyces sparsogenes;(E)-N-[(S)-1-(Hydroxymethyl)-2-[[(methylthio)methyl]sulfinyl]ethyl]-3-(1,2,3,4-tetrahydro-6-methyl-2,4-dioxopyrimidine-5-yl)propenamide;U-19183;2-Propenamide, N-[(1S)-1-(hydroxymethyl)-2-[(R)-[(methylthio)methyl]sulfinyl]ethyl]-3-(1,2,3,4-tetrahydro-6-methyl-2,4-dioxo-5-pyrimidinyl)-, (2E)-
3 prices
Selected condition：
Brand
- American Custom Chemicals Corporation
- Cayman Chemical
Package
- 1mg
- 5MG
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0015533
- Product descriptionSPARSOMYCIN 95.00%
- Packaging5MG
- Price$500.41
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number29934
- Product descriptionSparsomycin
- Packaging1mg
- Price$189
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number29934
- Product descriptionSparsomycin
- Packaging5mg
- Price$755
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| American Custom Chemicals Corporation | API0015533 | SPARSOMYCIN 95.00% | 5MG | $500.41 | 2021-12-16 | Buy |
| Cayman Chemical | 29934 | Sparsomycin | 1mg | $189 | 2024-03-01 | Buy |
| Cayman Chemical | 29934 | Sparsomycin | 5mg | $755 | 2024-03-01 | Buy |
Properties
Melting point :208-209° (dec)
alpha :D25 +69° (c = 0.5 in water)
Density :1.3893 (rough estimate)
refractive index :1.6390 (estimate)
storage temp. :2-8°C
solubility :DMF: soluble,DMSO: soluble,Ethanol: soluble,Methanol: soluble
form :A solid
pka :8.67 in water, 9.05 in 40% ethanol
color :White to off-white
alpha :D25 +69° (c = 0.5 in water)
Density :1.3893 (rough estimate)
refractive index :1.6390 (estimate)
storage temp. :2-8°C
solubility :DMF: soluble,DMSO: soluble,Ethanol: soluble,Methanol: soluble
form :A solid
pka :8.67 in water, 9.05 in 40% ethanol
color :White to off-white
Safety Information
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Description
Sparsomycin is a bacterial metabolite and a nucleoside analog of uracil that has been found in S. sparsogenes and has diverse biological activities. It is active against KB carcinoma cells, Gram-positive and Gram-negative bacteria, and fungi. Sparsomycin is an inhibitor of peptidyl transferase that interferes with tRNA binding to the A-site of the peptidyl transfer center and increases the binding of peptidyl-tRNA to the P-site. It inhibits protein synthesis in bacteria, archaea, and eukaryotes. Sparsomycin reduces tumor growth in a P388 mouse leukemia model and in a Walker 256 carcinosarcoma rat model.Related product price
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